ArtNr |
CSB-AP003491HO-5 |
Hersteller |
Cusabio
|
Menge |
5ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Lyophilized powder |
Specific against |
other |
Host |
E.coli |
Purity |
>95% as determined by SDS-PAGE and HPLC. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Interleukin-1 receptor antagonist protein,Short name:,IL-1RN,Short name:,IL-1ra,Short name:,IRAP,Alternative name(s):,IL1 inhibitor |
Lieferbar |
|
Classification |
Cytokine |
Subdivision |
Interleukin |
Research Areas |
Immunology |
Uniprot NO. |
O18999 |
Uniprot Entry Name |
IL1RA_HORSE |
Gene Names |
IL1RN |
Source |
E.Coli |
Expression Region |
26-177aa |
Sequence |
HPLGKRPCKM QAFRIWDVNQ KTFYMRNNQL VA GYLQESNT KLQEKIDVVP IEPDALFLGL HGRK LCLACV KSGDEIRFQL EAVNITDLSK NKEENK RFTF IRSNSGPTTS FESAACPGWF LCTAQEAD RP VSLTNKPKES FMVTKFYLQE DQ |
Protein Description |
Full Length of Mature Protein |
Tag Info |
Tag-Free |
Mol. Weight |
17.4 kDa |
Biological Activity |
Fully biologically active when compared to standard. The ED50 as determined by inhibiting IL-1alpha- dependent proliferation of murine D10S cells is less than 3.0 ug/ml, corresponding to a specific activity of ? 333 IU/mg in the presence of 50 pg/ml rHuIL-1alpha. |
Purity |
>95% as determined by SDS-PAGE and HPLC. |
Endotoxin |
Less than 1.0 EU/ug as determined by LAL method. |
Storage Buffer |
0.2 um filtered PBS, pH 7.4 , lyophilized |
Alias |
Interleukin-1 receptor antagonist protein Short name: IL-1RN Short name: IL-1ra Short name: IRAP Alternative name(s): IL1 inhibitor |
Relevance |
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. |
PubMed ID |
19157767 |
Function |
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. |
Subcellular Location |
Secreted |
Protein Families |
IL-1 family |
Tag Information |
Tag-Free |
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