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Recombinant Horse Interleukin-1 Receptor Antagonist protein(IL1RN) (Active)

Recombinant Horse Interleukin-1 Receptor Antagonist protein(IL1RN) (Active)

ArtNr	CSB-AP003491HO-100
Hersteller	Cusabio
Menge	100ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Lyophilized powder
Specific against	other
Host	E.coli
Purity	>95% as determined by SDS-PAGE and HPLC.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Interleukin-1 receptor antagonist protein,Short name:,IL-1RN,Short name:,IL-1ra,Short name:,IRAP,Alternative name(s):,IL1 inhibitor
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Classification	Cytokine
Subdivision	Interleukin
Research Areas	Immunology
Uniprot NO.	O18999
Uniprot Entry Name	IL1RA_HORSE
Gene Names	IL1RN
Source	E.Coli
Expression Region	26-177aa
Sequence	HPLGKRPCKM QAFRIWDVNQ KTFYMRNNQL VA GYLQESNT KLQEKIDVVP IEPDALFLGL HGRK LCLACV KSGDEIRFQL EAVNITDLSK NKEENK RFTF IRSNSGPTTS FESAACPGWF LCTAQEAD RP VSLTNKPKES FMVTKFYLQE DQ
Protein Description	Full Length of Mature Protein
Tag Info	Tag-Free
Mol. Weight	17.4 kDa
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by inhibiting IL-1alpha- dependent proliferation of murine D10S cells is less than 3.0 ug/ml, corresponding to a specific activity of ? 333 IU/mg in the presence of 50 pg/ml rHuIL-1alpha.
Purity	>95% as determined by SDS-PAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.4 , lyophilized
Alias	Interleukin-1 receptor antagonist protein Short name: IL-1RN Short name: IL-1ra Short name: IRAP Alternative name(s): IL1 inhibitor
Relevance	Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
PubMed ID	19157767
Function	Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
Subcellular Location	Secreted
Protein Families	IL-1 family
Tag Information	Tag-Free

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CSB-AP003491HO-100-datasheet.pdf

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