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Recombinant Human Granulocyte colony-stimulating factor protein(CSF3) (Active)

Recombinant Human Granulocyte colony-stimulating factor protein(CSF3) (Active)

ArtNr	CSB-AP002071HU-2
Hersteller	Cusabio
Menge	2ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Lyophilized powder
Specific against	other
Host	E.coli
Purity	>98% as determined by SDS-PAGE and HPLC.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	G-CSF, Filgrastim, Lenograstim
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Classification	Cytokine
Subdivision	Colony Stimulating Factor
Research Areas	Immunology
Uniprot NO.	P09919
Uniprot Entry Name	CSF3_HUMAN
Gene Names	CSF3, C17orf33, GCSF
Source	E.Coli
Expression Region	31-204aa
Sequence	TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQ EKLCATYK LCHPEELVLL GHSLGIPWAP LSSC PSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGIS PELG PTLDTLQLDV ADFATTIWQQ MEELGMAP AL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP
Protein Description	Partial of Isoform Short
Tag Info	Tag-Free
Mol. Weight	18.7 kDa
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine NFS-60 cells is less than 0.1 ng/ml, corresponding to a specific activity of ? 1.0 x 107 IU/mg.
Purity	>98% as determined by SDS-PAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered 10mM sodium acetate buffer, containing 5 % trehalose, pH 4.0 , lyophilized
Alias	G-CSF, Filgrastim, Lenograstim
Relevance	Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
PubMed ID	3484805; 2423327; 3494801; 15028279; 16625196; 2420009; 8554326; 7685769; 1281794; 7518249; 7685117; 10537111; 16492764
Function	Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
Subcellular Location	Secreted
Protein Families	IL-6 superfamily
Paythway	Jak-STATsignalingpathway
Tag Information	Tag-Free

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