ArtNr |
CSB-AP001151MO-500 |
Hersteller |
Cusabio
|
Menge |
500ug |
Quantity options |
1mg
100ug
20ug
250ug
5ug
500ug
|
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Lyophilized powder |
Specific against |
Mouse |
Purity |
>98% as determined by SDS-PAGE and HPLC. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Lieferbar |
|
Classification |
Cytokine |
Subdivision |
Chemokine |
Research Areas |
Immunology |
Uniprot NO. |
Q9JHH5 |
Uniprot Entry Name |
CXL11_MOUSE |
Gene Names |
Cxcl11, Scyb11 |
Source |
E.Coli |
Expression Region |
22-100aa |
Sequence |
FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YP SNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLI MQAIEK KNFLRRQNM |
Protein Description |
Full Length of Mature Protein |
Tag Info |
Tag-Free |
Mol. Weight |
9.1 kDa |
Biological Activity |
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using murine CXCR3 transfected 293 cells is in a concentration of 10-100 ng/ml. |
Purity |
>98% as determined by SDS-PAGE and HPLC. |
Endotoxin |
Less than 1.0 EU/ug as determined by LAL method. |
Storage Buffer |
0.2 um filtered PBS, pH 7.4 , lyophilized |
Alias |
Interferon-inducible T-cell alpha chemoattractant, Small-inducible cytokine B11 |
Relevance |
Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses (By similarity). {ECO:0000250}. |
PubMed ID |
10828609; 10843686 |
Function |
Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses (By similarity). |
Subcellular Location |
Secreted |
Protein Families |
Intercrine alpha (chemokine CxC) family |
Tag Information |
Tag-Free |
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