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Recombinant Macaca mulatta Interleukin-1 alpha(IL1A) (Active)

Recombinant Macaca mulatta Interleukin-1 alpha(IL1A) (Active)

ArtNr	CSB-AP003071MOW-1
Hersteller	Cusabio
Menge	1mg
Quantity options	1mg 10ug 100ug 2ug 250ug 500ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Lyophilized powder
Specific against	Monkey
Purity	>97% as determined by SDS-PAGE and HPLC.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
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Classification	Cytokine
Subdivision	Interleukin
Research Areas	Immunology
Uniprot NO.	P48089
Uniprot Entry Name	IL1A_MACMU
Gene Names	IL1A
Source	E.Coli
Expression Region	113-271aa
Sequence	SAPFSFLSNM TYHFIRIIKH EFILNDTLNQ TI IRANDQHL TAAAIHNLDE AVKFDMGAYT SSKD DTKVPV ILRISKTQLY VSAQDEDQPV LLKEMP EINK TITGSETNFL FFWETHGTKN YFISVAHP NL FIATKHDNWV CLAKGLPSIT DFQILENQA
Protein Description	Full Length of Mature Protein
Tag Info	Tag-Free
Mol. Weight	18.1 kDa
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 10 pg/ml, corresponding to a specific activity of ? 1.0 x 108 IU/mg.
Purity	>97% as determined by SDS-PAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.4 , lyophilized
Alias	IL-1 alpha,
Relevance	Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
PubMed ID	7561102
Function	Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.
Subcellular Location	Secreted
Protein Families	IL-1 family
Tag Information	Tag-Free

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