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Recombinant Human Rhombotin-1(LMO1),partial

ArtNr CSB-RP020544h-50
Hersteller Cusabio
Menge 50ug
Quantity options 1mg 10ug 100ug 20ug 200ug 50ug 500ug
Kategorie
Typ Proteins Recombinant
Format Liquid or Lyophilized powder
Specific against other
Host E.coli
Konjugat/Tag GST
Purity Greater than 90% as determined by SDS-PAGE.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Cysteine-rich protein TTG-1LIM domain only protein 1 ;LMO-1T-cell translocation protein 1
Lieferbar
Research Topic
Epigenetics and Nuclear Signaling
Uniprot ID
P25800
Gene Names
LMO1
Organism
Homo sapiens (Human)
AA Sequence
DKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKA LDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILC RRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVY HLDCFACQLCNQRFCVGDKFFLKNNMILCQMDYEE GQLNGTFESQVQ
Expression Region
5-156aa
Sequence Info
Partial
Source
E.coli
Tag Info
N-terminal GST-tagged
MW
44.4 kDa
Alternative Name(s)
Cysteine-rich protein TTG-1LIM domain only protein 1 ; LMO-1T-cell translocation protein 1
Relevance
May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors.
Reference
Human chromosome 11 DNA sequence and analysis including novel gene identification.Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. , Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y.Nature 440:497-500(2006)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage Buffer
Tris-based buffer, 50% glycerol
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors.
Involvement in disease
A chromosomal aberration involving LMO1 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(11, 14)(p15; q11) with TCRD.
Subcellular Location
Nucleus
Tissue Specificity
Expressed mainly in the central nervous. Low level of expression in other tissues including thymus.
Tag Information
N-terminal GST-tagged

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50ug
Lieferbar: In stock
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