Vergleich

Recombinant Human V-type proton ATPase subunit G 1(ATP6V1G1)

ArtNr CSB-RP001344h-200
Hersteller Cusabio
Menge 200ug
Quantity options 1mg 10ug 100ug 200ug 50ug 500ug
Kategorie
Typ Proteins Recombinant
Specific against other
Host E.coli
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias V-ATPase 13KDA subunit 1Vacuolar proton pump subunit G 1Vacuolar proton pump subunit M16
Lieferbar
Research Topic
Transport
Uniprot ID
O75348
Gene Names
ATP6V1G1
Organism
Homo sapiens (Human)
AA Sequence
ASQSQGIQQLLQAEKRAAEKVSEARKRKNRRLKQA KEEAQAEIEQYRLQREKEFKAKEAAALGSRGSCST EVEKETQEKMTILQTYFRQNRDEVLDNLLAFVCDI RPEIHENYRING
Expression Region
2-118aa
Sequence Info
Full Length of Mature Protein
Source
E.coli
Tag Info
N-terminal GST-tagged
MW
40.6 kDa
Alternative Name(s)
V-ATPase 13KDA subunit 1Vacuolar proton pump subunit G 1Vacuolar proton pump subunit M16
Relevance
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
Reference
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team Genome Res. 14:2121-2127(2004)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage Buffer
Tris-based buffer, 50% glycerol
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation
Protein Families
V-ATPase G subunit family
Tissue Specificity
Ubiquitous.
Paythway
mTORsignalingpathway

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200ug
Lieferbar: In stock
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