Vergleich

Recombinant Human Density-regulated protein(DENR)

ArtNr CSB-EP006724HU-200
Hersteller Cusabio
Menge 200ug
Kategorie
Typ Proteins Recombinant
Format Liquid or Lyophilized powder
Specific against other
Host E.coli
Purity Greater than 90% as determined by SDS-PAGE.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Protein DRP1Smooth muscle cell-associated protein 3 ;SMAP-3
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Research areas
Epigenetics and Nuclear Signaling
Target / Protein
DENR
Biologically active
Not Test
Expression system
E.coli
Species of origin
Homo sapiens (Human)
Uniprot ID
O43583
AA Sequence
AADISESSGADCKGDPRNSAKLDADYPLRVLYCGV CSLPTEYCEYMPDVAKCRQWLEKNFPNEFAKLTVE NSPKQEAGISEGQGTAGEEEEKKKQKRGGRGQIKQ KKKTVPQKVTIAKIPRAKKKYVTRVCGLATFEIDL KEAQRFFAQKFSCGASVTGEDEIIIQGDFTDDIID VIQEKWPEVDDDSIEDLGEVKK
Tag Info
N-terminal 6xHis-SUMO-tagged
Expression Region
2-198aa
Protein length
Full Length of Mature Protein
MW
38.0 kDa
Alternative Name(s)
Protein DRP1Smooth muscle cell-associated protein 3 ; SMAP-3
Relevance
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
References
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014)
Purity
Greater than 90% as determined by SDS-PAGE.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
Protein Families
DENR family
Tissue Specificity
Highly expressed in heart and skeletal muscle and moderately expressed in the brain, placenta, liver and pancreas. Weakly expressed in the lung and kidney.
Tag Information
N-terminal 6xHis-SUMO-tagged

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 200ug
Lieferbar: In stock
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