ArtNr |
CSB-AP002071HU-500 |
Hersteller |
Cusabio
|
Menge |
500ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Lyophilized powder |
Specific against |
Human |
Purity |
>98% as determined by SDS-PAGE and HPLC. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Lieferbar |
|
Classification |
Cytokine |
Subdivision |
Colony Stimulating Factor |
Research Areas |
Immunology |
Uniprot NO. |
P09919 |
Uniprot Entry Name |
CSF3_HUMAN |
Gene Names |
CSF3, C17orf33, GCSF |
Source |
E.Coli |
Expression Region |
31-204aa |
Sequence |
TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQ EKLCATYK LCHPEELVLL GHSLGIPWAP LSSC PSQALQ LAGCLSQLHS GLFLYQGLLQ ALEGIS PELG PTLDTLQLDV ADFATTIWQQ MEELGMAP AL QPTQGAMPAF ASAFQRRAGG VLVASHLQSF LEVSYRVLRH LAQP |
Protein Description |
Partial of Isoform Short |
Tag Info |
Tag-Free |
Mol. Weight |
18.7 kDa |
Biological Activity |
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine NFS-60 cells is less than 0.1 ng/ml, corresponding to a specific activity of ? 1.0 x 107 IU/mg. |
Purity |
>98% as determined by SDS-PAGE and HPLC. |
Endotoxin |
Less than 1.0 EU/ug as determined by LAL method. |
Storage Buffer |
0.2 um filtered 10mM sodium acetate buffer, containing 5 % trehalose, pH 4.0 , lyophilized |
Alias |
G-CSF, Filgrastim, Lenograstim |
Relevance |
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. |
PubMed ID |
3484805; 2423327; 3494801; 15028279; 16625196; 2420009; 8554326; 7685769; 1281794; 7518249; 7685117; 10537111; 16492764 |
Function |
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes. |
Subcellular Location |
Secreted |
Protein Families |
IL-6 superfamily |
Paythway |
Jak-STATsignalingpathway |
Tag Information |
Tag-Free |
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