ArtNr |
CSB-AP001961HU-500 |
Hersteller |
Cusabio
|
Menge |
500ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Lyophilized powder |
Specific against |
Human |
Purity |
>95% as determined by SDSPAGE and HPLC. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Lieferbar |
|
Classification |
Cytokine |
Subdivision |
Tumor Necrosis Factor |
Research Areas |
Cancer |
Uniprot NO. |
P41273 |
Uniprot Entry Name |
TNFL9_HUMAN |
Gene Names |
TNFSF9 |
Source |
E.Coli |
Expression Region |
71-254aa |
Sequence |
REGPELSPDD PAGLLDLRQG MFAQLVAQNV LL IDGPLSWY SDPGLAGVSL TGGLSYKEDT KELV VAKAGV YYVFFQLELR RVVAGEGSGS VSLALH LQPL RSAAGAAALA LTVDLPPASS EARNSAFG FQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE |
Protein Description |
Partial |
Tag Info |
Tag-Free |
Mol. Weight |
19.4 kDa |
Biological Activity |
Fully biologically active when compared to standard. The ED50 as determined by stimulation of IL8 production using human PBMC is less than 10 ng/ml, corresponding to a specific activity of ? 1.0 x 105 IU/mg. |
Purity |
>95% as determined by SDSPAGE and HPLC. |
Endotoxin |
Less than 1.0 EU/ug as determined by LAL method. |
Storage Buffer |
0.2 um filtered PBS, pH 7.4 , lyophilized |
Alias |
4-1BB ligand, |
Relevance |
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. {ECO:0000269|PubMed:20032458}. |
PubMed ID |
8088337; 15489334; 20032458 |
Function |
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. |
Subcellular Location |
Membrane, Single-pass type II membrane protein |
Protein Families |
Tumor necrosis factor family |
Tissue Specificity |
Expressed in brain, placenta, lung, skeletal muscle and kidney. |
Tag Information |
Tag-Free |
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