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Recombinant Human Interleukin-3 protein(IL3) (Active)

Recombinant Human Interleukin-3 protein(IL3) (Active)

ArtNr	CSB-AP001701HU-1
Hersteller	Cusabio
Menge	1mg
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Lyophilized powder
Specific against	Human
Purity	>96% as determined by SDS-PAGE and HPLC.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
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Classification	Cytokine
Subdivision	Interleukin
Research Areas	Immunology
Uniprot NO.	P08700
Uniprot Entry Name	IL3_HUMAN
Gene Names	IL3
Source	E.Coli
Expression Region	20-152aa
Sequence	APMTQTTSLK TSWVNCSNMI DEIITHLKQP PL PLLDFNNL NGEDQDILME NNLRRPNLEA FNRA VKSLQN ASAIESILKN LLPCLPLATA APTRHP IHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTL SL AIF
Protein Description	Full Length of Mature Protein
Tag Info	Tag-Free
Mol. Weight	15.0 kDa
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.1 ng/ml, corresponding to a specific activity of ? 1.0 x 107 IU/mg.
Purity	>96% as determined by SDS-PAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.4 , lyophilized
Alias	IL-3, Mast cell growth factor, MCGF, Multipotential colony-stimulating factor, P-cell-stimulating factor
Relevance	Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.; This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.
PubMed ID	3497843; 3127463; 3489530; 15372022; 15489334; 2544122; 8676386
Function	Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.; FUNCTION
Subcellular Location	Secreted
Protein Families	IL-3 family
Tissue Specificity	Activated T-cells, mast cells, natural killer cells.
Paythway	Jak-STATsignalingpathway
Tag Information	Tag-Free

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CSB-AP001701HU-1-datasheet.pdf

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