ArtNr |
CSB-PA792341 |
Hersteller |
Cusabio
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB, IF, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
DKFZp781D2042 antibody; FLJ42519 antibody; p65 antibody; SVP65 antibody; Synaptotagmin 2 antibody; Synaptotagmin I antibody; Synaptotagmin II antibody; Synaptotagmin-1 antibody; SYT antibody; Syt1 antibody; SYT1_HUMAN antibody; Syt2 antibody; SytI antibody, SYT1/2, SytI/II, Synaptotagmin I/II, P65, SYT |
Similar products |
P65, SYT, SYT1/2, SytI/II, Synaptotagmin I/II |
Lieferbar |
|
Immunogen Species |
Human |
UniprotID |
P21579/Q8N9I0 |
Immunogen |
Peptide sequence around aa.200ca.204/197ca.201 (R-K-T-L-N) derived from Human Synaptotagmin 1/2. |
Applications info |
ELISA, WB, IF, WB:1:500-1:1000, IF:1:100-1:200 |
Dilution ratio 1 |
ELISA:1:2000-1:10000 |
Dilution ratio 2 |
WB:1:500-1:1000 |
Dilution ratio 3 |
IF:1:100-1:200 |
Background |
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse
Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11, 105(10):3992-7. Cnops L, et al. Cereb Cortex. 2008 May, 18(5):1221-31. Lynch KL, et al. Mol Biol Cell. 2007 Dec, 18(12):4957-68. |
Conjugate |
Non-conjugated |
Buffer |
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
General Research Areas |
Neuroscience, Signal transduction |
Initial Research Areas |
Neuroscience |
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