PSMB7 Antibody

Q99436

ELISA, WB, IHC, ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

WB:1:500-1:2000

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14.

-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Antigen affinity purification

Signal Transduction