ArtNr |
CSB-PA558008-50ul |
Hersteller |
Cusabio
|
Menge |
50ul |
Quantity options |
100ul
50ul
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB, IHC, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Macropain chain Z antibody; Multicatalytic endopeptidase complex chain Z antibody; Proteasome (prosome macropain) subunit beta type 7 antibody; Proteasome beta 7 subunit antibody; Proteasome catalytic subunit 2 antibody; Proteasome subunit alpha antibody; Proteasome subunit beta 7 antibody; Proteasome subunit beta type-7 antibody; Proteasome subunit Z antibody; PSB7_HUMAN antibody; PSMB7 antibody; PUP1 antibody; Z antibody, proteasome (prosome, macropain) subunit, beta type, 7 |
Similar products |
7, beta type, proteasome (prosome, macropain) subunit |
Lieferbar |
|
Immunogen Species |
Human |
UniprotID |
Q99436 |
Immunogen |
Fusion protein of human PSMB7 |
Applications info |
ELISA, WB, IHC, ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
Dilution ratio 1 |
ELISA:1:2000-1:5000 |
Dilution ratio 2 |
WB:1:500-1:2000 |
Dilution ratio 3 |
IHC:1:25-1:100 |
Background |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. A pseudogene of this gene is located on the long arm of chromosome 14. |
Conjugate |
Non-conjugated |
Buffer |
-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
Antigen affinity purification |
General Research Areas |
Cell biology, Metabolism, Signal transduction |
Initial Research Areas |
Signal Transduction |
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