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Phospho-VCL (Tyr822) Antibody

ArtNr CSB-PA177557
Hersteller Cusabio
Menge 100ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, ELISA
Specific against Human, Mouse, Rat
Host Rabbit
Isotype IgG
ECLASS 5.1 32160702
ECLASS 6.1 32160702
ECLASS 8.0 32160702
ECLASS 9.0 32160702
ECLASS 10.0.1 32160702
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CMD1W antibody; CMH15 antibody; Epididymis luminal protein 114 antibody; HEL114 antibody; Metavinculin antibody; MV antibody; MVCL antibody; OTTHUMP00000019861 antibody; OTTHUMP00000019862 antibody; VCL antibody; VINC antibody; VINC_HUMAN antibody; Vinculin antibody, Vinculin,
Similar products Vinculin
Lieferbar
Immunogen Species
Human
UniprotID
P18206
Immunogen
Peptide sequence around phosphorylation site of Tyrosine 822 (S-G-Y(p)-R-I) derived from Human Vinculin.
Applications info
ELISA, WB, WB:1:500-1:1000
Dilution ratio 1
ELISA:1:2000-1:10000
Dilution ratio 2
WB:1:500-1:1000
Background

Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.

Subauste MC, et al. (2004) J Cell Biol 165, 371-81
Olsen JV, et al. (2010) Sci Signal 3, ra3
J rgensen C, et al. (2009) Science 326, 1502-9

Conjugate
Non-conjugated
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage
Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
General Research Areas
Isotype/Loading Controls, Cardiovascular, Signal transduction
Initial Research Areas
Signal Transduction

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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