ArtNr |
CSB-PA071225-50ul |
Hersteller |
Cusabio
|
Menge |
50ul |
Quantity options |
100ul
50ul
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
IHC, ELISA |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
DKFZp781H1925 antibody; E2AK3_HUMAN antibody; EC 2.7.11.1 antibody; Eif2ak3 antibody; Eukaryotic translation initiation factor 2 alpha kinase 3 antibody; Eukaryotic translation initiation factor 2-alpha kinase 3 antibody; Heme regulated EIF2 alpha kinase antibody; HRI antibody; HsPEK antibody; Pancreatic eIF2 alpha kinase antibody; Pancreatic eIF2-alpha kinase antibody; PEK antibody; PRKR like endoplasmic reticulum kinase antibody; PRKR-like endoplasmic reticulum kinase antibody; WRS antibody, eukaryotic translation initiation factor 2-alpha kinase 3 |
Similar products |
eukaryotic translation initiation factor 2-alpha kinase 3 |
Lieferbar |
|
Immunogen Species |
Human |
UniprotID |
Q9NZJ5 |
Immunogen |
Fusion protein of human EIF2AK3 |
Applications info |
ELISA, IHC, ELISA:1:1000-1:5000, IHC:1:25-1:100 |
Dilution ratio 1 |
ELISA:1:1000-1:5000 |
Dilution ratio 2 |
IHC:1:25-1:100 |
Background |
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
Conjugate |
Non-conjugated |
Buffer |
-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
Antigen affinity purification |
General Research Areas |
Epigenetics and Nuclear Signaling, Metabolism |
Initial Research Areas |
Epigenetics and Nuclear Signaling |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.