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FRS2 (Ab-196) Antibody

FRS2 (Ab-196) Antibody

ArtNr	CSB-PA208276
Hersteller	Cusabio
Menge	100ul
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies By Cell Type Sarcoma Western Blot ELISA Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human, Mouse
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	FGFR signaling adaptor SNT antibody; FGFR signalling adaptor antibody; FGFR substrate 2 antibody; FGFR-signaling adaptor SNT antibody; Fibroblast growth factor receptor substrate 2 antibody; FRS 2 antibody; FRS2 antibody; FRS2_HUMAN antibody; FRS2A antibody; FRS2alpha antibody; SNT 1 antibody; SNT antibody; SNT-1 antibody; SNT1 antibody; Suc 1 Associated Neurotrophic Factor Target antibody; Suc1 associated neurotrophic factor target 1 antibody; Suc1-associated neurotrophic factor target 1 antibody, FGFR signalling adaptor, FGFR signalling adaptor SNT-1, SNT-1, SNT2, SUC1-associated neurotrophic factor target
Similar products	SNT-1, FGFR signalling adaptor, SNT2, FGFR signalling adaptor SNT-1, SUC1-associated neurotrophic factor target
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Immunogen Species	Human
UniprotID	Q8WU20
Immunogen	Synthesized non-phosphopeptide derived from human FRS2 around the phosphorylation site of tyrosine 196 (H-T-Y(p)-V-N).
Applications info	ELISA, WB, WB:1:500-1:3000
Dilution ratio 1	ELISA:1:2000-1:10000
Dilution ratio 2	WB:1:500-1:3000
Background	Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1. The MGC Project Team, Genome Res. 14:2121-2127(2004). Xu H., J. Biol. Chem. 273:17987-17990(1998). Meakin S.O., J. Biol. Chem. 274:9861-9870(1999).
Conjugate	Non-conjugated
Buffer	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage	Upon receipt, store at -20C or -80C. Avoid repeated freeze.
Purification Method	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
General Research Areas	Signal transduction
Initial Research Areas	Signal Transduction

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100ul

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Lieferung vsl. bis 04.10.2024

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