ArtNr |
CSB-PA613427ESR1HU-50ul |
Hersteller |
Cusabio
|
Menge |
50ul |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
ATX antibody; ATX X antibody; Autotaxin antibody; Autotaxin t antibody; E NPP 2 antibody; E-NPP 2 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase 2 antibody; Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 antibody; Enpp2 antibody; ENPP2_HUMAN antibody; Extracellular lysophospholipase D antibody; FLJ26803 antibody; LysoPLD antibody; NPP2 antibody; PD IALPHA antibody; PDNP2 antibody; Phosphodiesterase I alpha antibody; Phosphodiesterase I/nucleotide pyrophosphatase 2 antibody; Plasma lysophospholipase D antibody, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2) (EC 3.1.4.39) (Autotaxin) (Extracellular lysophospholipase D) (LysoPLD), ENPP2, ATX PDNP2 |
Similar products |
ENPP2, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (E-NPP 2) (EC 3.1.4.39) (Autotaxin) (Extracellular lysophospholipase D) (LysoPLD), ATX PDNP2 |
Lieferbar |
|
Immunogen Species |
Human |
UniprotID |
Q13822 |
Immunogen |
Recombinant Human Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 protein (564-863AA) |
Applications info |
ELISA, IHC, Recommended dilution: IHC:1:20-1:200 |
Dilution ratio 1 |
ELISA:1:2000-1:10000 |
Dilution ratio 2 |
IHC:1:20-1:200 |
Background |
Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor. |
Conjugate |
Non-conjugated |
Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
Antigen Affinity Purified |
General Research Areas |
Neuroscience, Cancer, Cardiovascular, Metabolism, Signal transduction |
Initial Research Areas |
Cardiovascular |
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