Hersteller |
Cusabio
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Specific against |
Human |
Isotype |
IgG |
Format |
Liquid |
Applikationen |
WB, IHC, ELISA |
Menge |
50ul |
Host |
Rabbit |
ArtNr |
CSB-PA123979-50ul |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Lieferbar |
|
Alias |
A kinase (PRKA) anchor protein (gravin) 12 antibody; A kinase Anchor Protein 12 antibody; A kinase anchor protein 250kDa antibody; A-kinase anchor protein 12 antibody; A-kinase anchor protein 250 kDa antibody; AKA12_HUMAN antibody; AKAP 12 antibody; AKAP 250 antibody; AKAP-12 antibody; Akap12 antibody; AKAP250 antibody; DKFZp686M0430 antibody; DKFZp686O0331 antibody; FLJ20945 antibody; FLJ97621 antibody; Gercelin antibody; Gravin antibody; Kinase scaffold protein gravin antibody; Myasthenia gravis autoantigen antibody; Myasthenia gravis autoantigen gravin antibody; OTTHUMP00000017426 antibody; OTTHUMP00000017427 antibody; Src-Suppressed C Kinase Substrate antibody; Srcs5 antibody; SSeCKS antibody; Tsga12 antibody, A kinase (PRKA) anchor protein 12 |
Immunogen Species |
Human |
UniprotID |
Q02952 |
Immunogen |
Synthetic peptide of human AKAP12 |
Applications info |
ELISA, WB, IHC, ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 |
Dilution ratio 1 |
ELISA:1:1000-1:2000 |
Dilution ratio 2 |
WB:1:200-1:1000 |
Dilution ratio 3 |
IHC:1:50-1:200 |
Background |
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Conjugate |
Non-conjugated |
Buffer |
-20C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
Antigen affinity purification |
General Research Areas |
Neuroscience, Signal transduction |
Initial Research Areas |
Signal Transduction |
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