ArtNr |
CSB-PA019872ESR1HU-50ul |
Hersteller |
Cusabio
|
Menge |
50ul |
Quantity options |
100ul
50ul
|
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
WB, IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
FLJ38841 antibody; Hypothetical protein LOC285498 antibody; LOC285498 antibody; OTTHUMP00000147525 antibody; Probable E3 SUMO-protein ligase RNF212 antibody; RING finger protein 212 antibody; RN212_HUMAN antibody; RNF 212 antibody; RNF212 antibody; ZHP3 antibody; ZHP3; C. elegans; homolog of antibody; ZIP3-related protein antibody, Probable E3 SUMO-protein ligase RNF212 (EC 2.3.2.-) (Probable E3 SUMO-protein transferase RNF212) (RING finger protein 212), RNF212 |
Similar products |
RNF212, Probable E3 SUMO-protein ligase RNF212 (EC 2.3.2.-) (Probable E3 SUMO-protein transferase RNF212) (RING finger protein 212) |
Lieferbar |
|
Immunogen Species |
Human |
UniprotID |
Q495C1 |
Immunogen |
Recombinant Human Probable E3 SUMO-protein ligase RNF212 protein (1-297AA) |
Applications info |
ELISA, WB, IHC, Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200 |
Dilution ratio 1 |
ELISA:1:2000-1:10000 |
Dilution ratio 2 |
WB:1:200-1:1000 |
Dilution ratio 3 |
IHC:1:20-1:200 |
Background |
SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination (By similarity). |
Conjugate |
Non-conjugated |
Buffer |
PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Storage |
Upon receipt, store at -20C or -80C. Avoid repeated freeze. |
Purification Method |
Antigen Affinity Purified |
General Research Areas |
Epigenetics and Nuclear Signaling |
Initial Research Areas |
Epigenetics and Nuclear Signaling |
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