ArtNr |
CSB-PA006237LD01HU |
Hersteller |
Cusabio
|
Menge |
100ug |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Liquid |
Applikationen |
ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Coxsackievirus and adenovirus receptor,CAR,hCAR,CXADR,CAR,CVB3-binding protein,Coxsackievirus B-adenovirus receptor,HCVADR |
Lieferbar |
|
Background |
Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. |
Alias |
Coxsackievirus and adenovirus receptor, CAR, hCAR, CXADR, CAR, CVB3-binding protein, Coxsackievirus B-adenovirus receptor, HCVADR |
Uniprot |
P78310 |
Immuongen |
Recombinant human Coxsackievirus and adenovirus receptor protein (259-365AA) |
Counjugation |
Biotin |
Buffer |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Storage |
Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze. |
Purification |
Caprylic Acid Ammonium Sulfate Precipitation purified |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.