Human Monkey Anti-Bovine Type II Collagen IgA Antibody Assay Kit, TMB

The Collagen-Induced Arthritis (CIA) monkey model uses injections of complete Freund's adjuvant (CFA) emulsified with heterologous type II collagen to induce autoimmune arthritis. The development of antibodies to the heterologous collagen used for immunization is an important factor in the development of the CIA model. Given the highly conserved sequence of type II collagen, the antibodies against the immunized collagen can cross-react to autologous type II collagen in the experimental animal. This kit allows for the chartacterization of the immune response to immunization of bovine type II collagen in the monkey CIA model.

Human/Monkey anti-bovine type II collagen IgA antibodies

Rheumatoid arthritis / autoimmune arthritis models

ELISA kit for the quantification of human/monkey IgA antibodies against bovine type II collagen in human/monkey serum samples. This kit uses TMB as the chromagen.