ArtNr |
CS-CSI20129B |
Hersteller |
Cell Sciences
|
Menge |
10 ug |
Kategorie |
|
Typ |
Proteins |
Specific against |
Mouse (Murine, Mus musculus) |
Host |
E.coli |
Purity |
>98% by SDS-PAGE and HPLC analyses. |
Sequence |
SIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSKI |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
IL-33, C9orf26, DKFZp586H0523, DVS27, NF-HEV, NFEHEV, RP11-575C20.2, DVS27-related protein, nuclear factor from high endothelial venules, IL-1F11, interleukin-33, interleukin-1 family member 11 |
Lieferbar |
|
Manufacturer - Category |
Biomolecules |
Storage Conditions |
This lyophilized preparation is stable at 2-4C, but should be kept desiccated at -20C for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-4C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -80C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
Approximately 17.5 kDa protein containing 158 amino acid residues. |
Description |
Recombinant Mouse Interleukin-33 (IL-33) is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. |
Formulation |
Lyophilized from a 0.2 um filtered solution in PBS, EDTA and DTT. |
Reconstitution |
Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions. |
Specificity |
2 x 106 units/mg |
Biological Activity |
Fully biologically active when compared to standard. The ED50 determined by a cell proliferation assay usingmouse D10S cells is less than 0.5 ng/ml |
Endotoxin Level |
Less than 1EU/ug of rMuIL-33 as determined by LAL method. |
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