Vergleich

Recombinant Mouse Thrombopoietin

ArtNr CS-CSI12329
Hersteller Cell Sciences
Menge 10 ug
Kategorie
Typ Proteins
Specific against Mouse (Murine, Mus musculus)
Host E.coli
Purity >98% by SDS-PAGE and HPLC analyses. Endotoxin level is <0.1 ng per ug of TPO.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products TPO, myeloproliferative leukemia virus oncogene ligand, Mpllg, TPO-1, TPO-2, TPO-3, TPO-4, OTTMUSP00000023070, OTTMUSP00000023071
Lieferbar
Biological Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells is < 1.0 ng/ml, corresponding to a specific activity of > 1 x 106 units/mg.
Description
TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets, in vivo . TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and mouse TPO exhibits cross-species reactivity. Recombinant mouse TPO is a fully biologically active 174 amino acid polypeptide (18.7 kDa), which contains the erythropoietin-like domain of the full length TPO protein.
Formulation
Sterile filtered and lyophilized from 10 mM Tris, pH 8.0.
Molecular Weight
18.7 kDa
Reconstitution
Centrifuge vial prior to opening. The mouse TPO should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20C.
Storage and Stability
The lyophilized TPO should be stored desiccated below 0C. Reconstituted TPO should be stored in working aliquots at -20C. Avoid repeated freeze-thaw cycles.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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