Similar products |
AEPLC, ALP56, ASP21, ASP1, BAE2, CDA13, CEAP1, DRAP, 56 kDa aspartic-like protease, Down syndrome region aspartic protease, aspartyl protease 1, beta secretase 2, beta-site amyloid beta A4 precursor protein-cleaving enzyme 2, memapsin-1, membrane-associated aspartic protease 1, transmembrane aspartic proteinase Asp1 |
Description |
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. |
Formulation |
It is supplied as 200 ug/ml, 50 ug/vial, in PBS pH7.2 (10 mM NaH2PO4, 10 mM, Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.. Precaution: Sodium azide is a poisonous and hazardous substance which should be handled by trained staff only. |