Native Human Apotransferrin, Tissue Culture Grade

Transferrin (TF) is a glycoprotein thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C- and N-terminal domains each of which binds one ion of Ferric Iron. Therefore, each Human TF molecule has the ability to carry two Iron ions in the Ferric form (Fe3+). The function of TF is to transport Iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. TF may also have a physiologic role as Granulocyte/Pollen-Binding Protein (GPBP) involved in the removal of certain organic matter and allergens from serum. Apo-Transferrin designates the form of the molecule without Iron bound. Like TF, APO-TF has a physiological role in the transportation and distribution of Iron among the body organs. It is also an important transport factor used in defined culture media.

76.5 kDa

Store at -80C. 3 years from delivery. Avoid repeated freeze-thaw cycles .