Recombinant Human SOD1

Human Cu/Zn Superoxide Dismutase (SOD1) catalyzes the reaction between superoxide anions and hydrogen to yield molecular oxygen and hydrogen peroxide. The enzyme protects the cell against dangerous levels of superoxide. SOD1 binds copper and zinc ions and is 1 of 3 isozymes accountable for destroying free superoxide radicals in the body. The encoded protein neutralizes supercharged oxygen molecules, which can damage cells if their levels are not controlled. Mutations in SOD1 cause a form of familial amyotrophic lateral sclerosis. Recombinant Human Cu/Zn Superoxide Dismutase produced in, E. coli, is a homodimer, non-glycosylated polypeptide chain containing 2 x 154 amino acids.

31, 608 Dalton

Lyophilized SOD although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution SOD should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.