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Recombinant Human soluble TRAIL/APO2L

Recombinant Human soluble TRAIL/APO2L

ArtNr	CS-CRT500B
Hersteller	Cell Sciences
Menge	50 ug
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes Peptides & Proteins Recombinant Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Cardiovascular Research Ischemia & Reperfusion Injury
Typ	Proteins
Specific against	Human (Homo sapiens)
Host	E.coli
Purity	Greater than 90.0% as determined by HPLC, Reducing and Non-reducing SDS-PAGE, UV spectroscopy at 280 nm
Sequence	MRERGPQRVA AHITGTRGRS NTLSSPNSKN EKALGRKINS WESSRSGHSF LSNLHLRNGE LVIHEKGFYY IYSQTYFRFQ EEIKENTKND KQMVQYIYKY TSYPDPILLM KSARNSCWSK DAEYGLYSIY QGGIFELKEN DRIFVSVTNE HLIDMDHEAS FFGAFLVG
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Similar products	TRAIL, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, CD253, APO2L, member 10, TL2, TNF-related apoptosis inducing ligand TRAIL, tumor necrosis factor (ligand) family, tumor necrosis factor ligand superfamily member 10, tumor necrosis factor apoptosis-inducing ligand splice variant delta
Lieferbar
Manufacturer - Category	Biomolecules
Storage Conditions	Lyophilized product is very stable at -20C. Reconstituted material should be aliquoted and frozen at -20C. It is recommended that a carrier protein such as 0.1% HSA or BSA be added for long term storage. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.
Molecular Weight	19.5 kDa
Description	TNF-Related Apoptosis-Inducing Ligand (TRAIL) is produced by a wide variety of cell types and is shown to be a cytotoxic protein that induces apoptosis in tumor cells through activation of the death receptors, DR4 and DR5. Human TRAIL is active on mouse cells. Recombinant human TRAIL is a non-glycosylated protein, containing the 168 amino acid extracellular portion of TRAIL that is homologous to TNF.
Formulation	Lyophilized from a sterile filtered solution of 10 mM Na2PO4, pH 7.5, + 50 mM NaCl.
Reconstitution	Centrifuge vial prior to opening. When reconstituting the product, gently pipet and wash down the sides of the vial to ensure full recovery of the protein into solution. It is recommended to reconstitute the lyophilized product with sterile water at a concentration of 0.1 mg/ml. After complete solubilization of the protein, it can be further diluted to other aqueous solutions.
Biological Activity	The activity is determined by the ability to induce apoptotic cell death in TRAIL-sensitive RPMI-8226 cells and is typically 10-15 ng/mL.
Endotoxin Level	Measured by kinetic LAL analysis and is typically <=1 EU/ug protein.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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CS-CRT500B-datasheet.pdf

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Menge: 50 ug

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Lieferung vsl. bis 08.05.2025

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