Native Human D-Dimer

Native human D-dimer. Human D-Dimer protein is a blood test performed in the medicallaboratory to diagnose thrombosis. Since human D-Dimer(s) introduction, human DDimerprotein has become an important test performed in patients suspected ofthrombotic disorders. While a negative human D-Dimer result practically rules outthrombosis, a positive human D-Dimer result can indicate thrombosis but also has otherpotential causes. Human D-Dimer(s) main use is to exclude thromboembolic diseasewhere the probability is low. Human D-dimer testing is of clinical use when there is asuspicion of deep venous thrombosis (DVT) or pulmonary embolism (PE). In patientssuspected of disseminated intravascular coagulation (DIC), Human D-dimer(s) proteinmay aid in the diagnosis. Human D-dimer(s) protein are unique in that they are thebreakdown products of a fibrin mesh that has been stabilized by Factor XIII. This factorcrosslinks the E-element to two D-elements. This is the final step in the generation of athrombus.

ca.200 kDa