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Recombinant Human Cytokeratin 14

ArtNr CS-CRC175B
Hersteller Cell Sciences
Menge 20 ug
Kategorie
Typ Proteins
Specific against Human (Homo sapiens)
Host E.coli
Purity > 95% as determined by SDS-PAGE and RP-HPLC analyses
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products CK14, EBS3, EBS4, K14, NFJ, cytokeratin 14, keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner)
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Description
Cytokeratin 14 is a member of the keratin family, the most diverse group of intermediate filaments. Cytokeratin 14 is a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.
Endotoxin Level
< 0.1 ng/ug of KRT14
Formulation
Lyophilized from a sterile filtered solution containing 30 mM Tris-HCl, pH 8.0 + 9.5 M urea + 2 mM DTT + 2 mM EDTA + 10 mM methylammonium chloride
Molecular Weight
51.53 kDa
Reconstitution
Centrifuge vial prior to opening. First add sterile distilled water to the vial to fully solubilize the protein to a concentration not less than 100 ug/ml. After complete solubilization of the protein, it can be further diluted to other aqueous solutions.
Storage and Stability
Store lyophilized protein at -20C to -80C. Reconstituted protein is stable for 1 week at 2-4C. For long term storage, aliquot and store at -20C to -80C with a carrier protein (0.1% HSA or BSA) as a stabilizer. Please note that the addition of any carrier protein into this product may produce unwanted endotoxin. This depends upon the particular application employed. Avoid repeated freeze-thaw cycles.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20 ug
Lieferbar: In stock
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