ArtNr |
CS-CRA007B |
Hersteller |
Cell Sciences
|
Menge |
50 ug |
Kategorie |
|
Typ |
Proteins |
Specific against |
Human (Homo sapiens) |
Host |
E.coli |
Purity |
> 95% as determined by SDS-PAGE and RP-HPLC analyses |
Sequence |
VYLSECKTGN GKNYRGTMSK TKNGITCQKW SSTSPHRPRF SPATHPSEGL EENYCRNPDN DPQGPWCYTT DPEKRYDYCD ILECEEECMH CSGENYDGKI SKTMSGLECQ AWDSQSPHAH GYIPSKFPNK NLKKNYCRNP DRELRPWCFT TDPNKRWELC DIPRCTTPPP SSGPTYQCLKGTGENYRGNV AVTVSGHTCQ HWSAQTPHTH NRTPENFPCK NLDENYCRNP DGK |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
DKFZp779M0222, OTTHUMP00000017544 |
Lieferbar |
|
Biological Activity |
Fully biologically active when compared to standard. The specific activity determined by an assay on anti-proliferation and anti-migration using endothelial cells, in vitro, and anti-angiogenesis, in vivo, is 5.5 x 10E5 IU/mg. |
Description |
Angiostatin K1-3 is a ca.30 kDa fragment of plasminogen that has been shown to act as a potent inhibitor of angiogenesis and tumor growth, in vitro, and, in vivo . |
Endotoxin Level |
Less than 1EU/ug of rHuAngiostatin K1-3 as determined by LAL method. |
Formulation |
Lyophilized from a 0.2 um filtered concentrated solution in 20 mM NaAc, pH5.5 + 4% mannitol. |
Molecular Weight |
30.0 kDa |
Reconstitution |
Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/ml. Further dilutions should be made in appropriate buffered solutions. |
Storage and Stability |
This lyophilized preparation is stable at 2-4C, but should be kept desiccated at -20C for long term storage. Upon reconstitution, the preparation is stable for up to one week at 2-4C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20C to -80C. Avoid repeated freeze/thaw cycles. |
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