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IL-6, HGF, IL6, IFNB2, B-cell stimulatory factor 2, CTL differentiation factor, BSF-2, CDF, IFN-beta-2, BSF2, HSF, B cell stimulatory factor-2, B-cell differentiation factor, OTTHUMP00000158544, hybridoma growth factor, interleukin BSF-2, interleukin-6, interferon beta-2, OTTHUMP00000198486, OTTHUMP00000198490 |
Description |
Interleukin-6 (IL-6) is a cytokine that functions in inflammation and the maturation of B-cells. IL-6 is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through Interleukin-6 Receptor alpha (IL6R). The functioning of IL-6 is implicated in a wide variety of inflammation-associated disease states, including susceptibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. |