Mouse Anti-Human VEGFR-2/KDR Clone 4H3 mAb

Mouse Anti-Human VEGFR-2/KDR Clone 4H3 monoclonal antibody. Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. VEGF recptor 2 is one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, and T-cell protein tyrosine phosphatase.

Recombinant Human soluble extracellular KDR (D7)

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1-1.0 mg/ml.

Detects Native Human KDR/VEGFR-2 on the surface of different human cell types.