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Mouse Anti-Human CD300a Clone MEM-260 PE mAb

ArtNr CS-CMC412
Hersteller Cell Sciences
Menge 100 tests
Kategorie
Typ Antibody Monoclonal
Applikationen FC
Clon MEM-260
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1
Purity The conjugate is purified by size-exclusion chromatography.
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Similar products CD300A, CMRF-35-H9, CMRF-35H, CMRF35H, CMRF35H9, IGSF12, IRC1, IRC2, IRp60, CD300a antigen, CMRF35H leukocyte immunoglobulin-like receptor, leukocyte membrane antigen
Lieferbar
Manufacturer - Category
Antibodies
Storage Conditions
Store in the dark at 2-4C. Do not freeze. Avoid prolonged exposure to light. When stored as instructed, product is stable for one year.
Description
Mouse Anti-Human CD300a Clone MEM-260 Monoclonal Antibody conjugated to R-PE. CD300a (CMRF-35H, IRp60) is a non-MHC-specific inhibitory receptor of immunoglobulin superfamily, which contains three immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that associate with SH2-containing phosphatases SHP-1 and SHP-2. CD300a is expressed on many cell types including T cells, NK cells, neutrophils, eosinophils or mast cells. Its triggering inhibits activating signals such as those of IL5, GM-CSF or eotaxin, as well as supresses mast cell degranulation or NK cell cytotoxic activity.
Formulation
Liquid in phosphate buffered saline (PBS) containing 15 mM sodium azide + 0.2% (w/v) BSA as a stabilizing agent.
Immunogen
HPB human acute lymphoid leukemia cell line
Specificity
Reacts with CD300a, a 60 kDa leukocyte transmembrane glycoprotein expressed on human granulocytes, monocytes, neutrophils, NK cells, mast cells and dendritic cells, 25% of circulating T-cells and 15% of circulating B-cells.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 tests
Lieferbar: In stock
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