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NEDD8 Neural Precursor Cell Expressed Developmentally Down-Regulated 8 Human Recombinant Protein

NEDD8 Neural Precursor Cell Expressed Developmentally Down-Regulated 8 Human Recombinant Protein

ArtNr	BOS-PROTQ15843
Hersteller	Boster
Menge	25ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solution
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	NEDD8;Neddylin;Neural precursor cell expressed developmentally down-regulated protein 8;NEDD-8;Ubiquitin-like protein Nedd8;NEDD8;
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Contents	The NEDD8 solution contains 20mM Tris pH 8.0, 50mM NaCl, 0.5mM DTT & 10% glycerol.
Description	NEDD8 Human Recombinant fused with 37 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 113 amino acids (1-76 a.a.) and having a molecular mass of 12.8 kDa. The NEDD8 is purified by proprietary chromatographic techniques.
Gene name	NEDD8
Protein function	Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C- APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.
Purification	Greater than 95.0% as determined by SDS-PAGE.
Shipping	Shipped with wet ice
Short description	NEDD8 Human Recombinant fused with 37 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 113 amino acids (1-76 a.a.) and having a molecular mass of 12.8 kDa. The NEDD8 is purified by proprietary chromatographic techniques.
Storage	Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles.
Subcellular localization	Nucleus
Tissue specificity	Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes.
Format Information	Sterile Filtered colorless solution.

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Menge: 25ug

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Lieferung vsl. bis 30.08.2024

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