ArtNr |
BOS-PROTP20138 |
Hersteller |
Boster
|
Menge |
20ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Solution |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Myeloid cell surface antigen CD33;Sialic acid-binding Ig-like lectin 3;Siglec-3;gp67;CD33;CD33;SIGLEC3; |
Lieferbar |
|
Contents |
CD33 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea, and 10% glycerol. |
Description |
CD33 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 265 amino acids (18-259 a.a) and having a molecular mass of 29.1kDa.CD33 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Gene name |
CD33 |
Protein function |
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2, 6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). |
Purification |
Greaterthan 90% as determined by SDS-PAGE. |
Shipping |
Shipped with wet ice |
Short description |
CD33 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 265 amino acids (18-259 a.a) andhaving a molecular mass of 29.1kDa.CD33 is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques. |
Storage |
Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles. |
Subcellular localization |
Cell membrane; Single-pass type I membrane protein. |
Tissue specificity |
Monocytic/myeloid lineage cells. |
Format Information |
Sterile Filtered clear solution. |
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