ArtNr |
BOS-EKC2332 |
Hersteller |
Boster
|
Menge |
1 kit, containing two 96-well plates and all necessary reagents |
Kategorie |
|
Typ |
Elisa-Kit |
Applikationen |
ELISA |
Specific against |
Human, Mouse, Rat |
Sensitivity |
>5000 cells |
ECLASS 10.1 |
32160605 |
ECLASS 11.0 |
32160605 |
UNSPSC |
41116126 |
Alias |
Casein kinase I isoform alpha;CKI-alpha;2.7.11.1;CK1;CSNK1A1; |
Lieferbar |
|
Manufacturers Product Category |
Cell-Based ELISA Kits |
Short Description |
The Casein Kinase I alpha (Phospho-Tyr321) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Casein Kinase I alpha (Phospho-Tyr321) protein expression profile in cells. The kit can be used for measuring the relative amounts of Casein Kinase I alpha (Phospho-Tyr321) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Casein Kinase I alpha (Phospho-Tyr321). |
Description |
The Casein Kinase I alpha (Phospho-Tyr321) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Casein Kinase I alpha (Phospho-Tyr321) protein expression profile in cells. The kit can be used for measuring the relative amounts of Casein Kinase I alpha (Phospho-Tyr321) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Casein Kinase I alpha (Phospho-Tyr321). |
Gene Name |
CSNK1A1 |
Storage |
Store at 4°C for up to 6 months. |
Gene Full Name |
Casein kinase I isoform alpha |
Molecular Weight |
38915 MW |
Protein Function |
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688). |
Subcellular Localization |
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus speckle. Cytoplasm, cytoskeleton, cilium basal body. Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. Also recruited to the keratin cytoskeleton (PubMed:23902688). |
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