ArtNr |
BOS-EK1227 |
Hersteller |
Boster
|
Menge |
96 wells/kit, with removable strips. |
Kategorie |
|
Typ |
Elisa-Kit |
Applikationen |
ELISA |
Specific against |
Mouse |
Sensitivity |
<1 pg/ml |
ECLASS 10.1 |
32160605 |
ECLASS 11.0 |
32160605 |
UNSPSC |
41116126 |
Alias |
Protein Tnfrsf14 ;Tumor necrosis factor receptor superfamily member 14 ;Tnfrsf14 ; |
Lieferbar |
|
Manufacturers Product Category |
PicoKine® ELISA Kits |
Manufacturers Research Category |
Antiviral Signaling, Cancer, Cytokines, Growth Factors, Growth Factors/Hormones, Immune System Diseases, Immunology, Innate Immunity, Signal Transduction, TNF Superfamily |
Short Description |
Mouse TNFRSF14/HVEM ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Tnfrsf14 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 1pg/ml. |
Description |
Mouse TNFRSF14/HVEM ELISA Kit PicoKine® (96 Tests). Quantitate Mouse Tnfrsf14 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 1pg/ml. |
Background |
Tumor necrosis factor receptor superfamily member 14 (TNFRSF14), also known as HVEM, is a protein that in humans is encoded by the TNFRSF14 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. It is mapped to 1p36.32. HVEM plays an important role in HSV pathogenesis because it enhanced the entry of several wildtype HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T cells. HVEM and BTLA which are form a bidirectional signaling pathway can regulate cell survival and inhibitory responses between interacting cells. HVEM as an important orchestrator of mucosal immunity integrates signals from innate lymphocytes to induce optimal epithelial Stat3 activation, which indicated that targeting HVEM with agonists could improve host defense. |
Gene Name |
TNFRSF14 |
Application Details |
Dilution ratio of 1:1, concentration in serum and plasma is 300-500 pg/ml. |
Immunogen |
Expression system for standard: CHO; Immunogen sequence: Q29-V207 |
Cross-reactivity |
There is no detectable cross-reactivity with other relevant proteins. |
Sample Type |
cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). |
Capture antibody|Detection antibody |
monoclonal antibody from rat|polyclonal antibody from goat |
Storage |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
Anticoagulant |
heparin or EDTA |
Gene Full Name |
tumor necrosis factor receptor superfamily, member 14 |
Molecular Weight |
30171 MW |
Protein Name |
Protein Tnfrsf14 |
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