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Human CD244/2B4 ELISA Kit PicoKine®

Human CD244/2B4 ELISA Kit PicoKine®

ArtNr	BOS-EK0926
Hersteller	Boster
Menge	96 wells/kit, with removable strips.
Kategorie	Oncology By Cell Type Carcinoma Hematology Myeloma Cell Biology Cell Status Apoptosis ELISA ELISA & Immunoassays ELISA Kits Immunoassay By Organ Lung Cancer Bladder Cancer Breast Cancer
Typ	Elisa-Kit
Applikationen	ELISA
Specific against	Human
Sensitivity	<10 pg/ml
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	Natural killer cell receptor 2B4;NK cell activation-inducing ligand;NAIL;NK cell type I receptor protein 2B4;NKR2B4;h2B4;SLAM family member 4;SLAMF4;Signaling lymphocytic activation molecule 4;CD244;CD244;2B4;
Lieferbar
Manufacturers Product Category	PicoKine® ELISA Kits
Manufacturers Research Category	Cell Type Markers, Hematopoietic Progenitors, Immunology, Lymphoid, NK Cells, Stem Cells, T Lymphocytic Lineage
Short Description	Human CD244/2B4 ELISA Kit PicoKine® (96 Tests). Quantitate Human CD244 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.
Description	Human CD244/2B4 ELISA Kit PicoKine® (96 Tests). Quantitate Human CD244 in cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA). Sensitivity: 10pg/ml.
Background	CD244 (Cluster of Differentiation 244) is a human protein encoded by the CD244 gene. It is also known as Natural Killer Cell Receptor 2B4. Members of the CD2 family adhere to each other instead, the cell surface glycoprotein 2B4 is related to CD2 and is implicated in the regulation of NK- and T-cell function. The 2B4 gene was mapped to 1q22 on gene map, where SLAM, CD48, CD84 and LY9 are also located. Using recombinant human NK cell-activating ligand 2B4 fused to domains 3 and 4 of rodent Cd4 and flow cytometric analysis, It was found that CD48 binds to 2B4. BIAcore surface plasmon resonance analysis showed that the affinity of CD48 for 2B4 is approximately 10-fold higher than that shown for CD48 and CD2.
Gene Name	CD244
Application Details	Dilution ratio of 1:1, concentration in serum and plasma is less than the lowest standard, 15.6 pg/ml.
Immunogen	Expression system for standard: NS0; Immunogen sequence: C22-R221
Cross-reactivity	There is no detectable cross-reactivity with other relevant proteins.
Sample Type	cell culture supernatants, cell lysates, serum and plasma (heparin, EDTA).
Capture antibody\|Detection antibody	monoclonal antibody from mouse\|polyclonal antibody from goat
Storage	Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Anticoagulant	heparin or EDTA
Gene Full Name	Natural killer cell receptor 2B4
Molecular Weight	41616 MW
Protein Function	Modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family..
Subcellular Localization	Membrane ; Single-pass type I membrane protein.
Tissue Specificity	Expressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils..
Protein Name	Natural killer cell receptor 2B4

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