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Horse equine TGF-Beta 2 ELISA Kit PicoKine®

Horse equine TGF-Beta 2 ELISA Kit PicoKine®

ArtNr	BOS-EK0981-EQ
Hersteller	Boster
Menge	96 wells/kit, with removable strips.
Kategorie	Oncology ELISA ELISA & Immunoassays ELISA Kits Immunoassay By Organ Brain Cancer
Typ	Elisa-Kit
Applikationen	ELISA
Specific against	Horse
Sensitivity	<10 pg/ml
ECLASS 10.1	32160605
ECLASS 11.0	32160605
UNSPSC	41116126
Alias	Transforming growth factor beta-2;TGF-beta-2;BSC-1 cell growth inhibitor;Cetermin;Glioblastoma-derived T-cell suppressor factor;G-TSF;Polyergin;Latency-associated peptide;LAP;TGFB2;
Lieferbar
Manufacturers Product Category	PicoKine® ELISA Kits
Manufacturers Research Category	Angiogenesis, Cancer, Cancer Metabolism, Cardiovascular, Developmental Biology, Growth Factors, Growth Factors/Hormones, Invasion/Microenvironment, Metabolism, Metabolism Processes, Organogenesis, Pathways and Processes, Response To Hypoxia, Secreted, Signal Transduction, Signaling Pathways, Stem Cells, TGF Beta
Short Description	Horse equine TGF-Beta 2 ELISA Kit PicoKine® (96 Tests). Quantitate Horse TGFB2 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 10pg/ml.
Description	Horse equine TGF-Beta 2 ELISA Kit PicoKine® (96 Tests). Quantitate Horse TGFB2 in cell culture supernatants, serum and plasma (heparin, EDTA, citrate). Sensitivity: 10pg/ml.
Background	Transforming growth factor-beta 2 (TGF-beta 2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development. This gene is mapped to 1q41. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. TGF-beta 2 is present at elevated levels in the aqueous humor of patients with primary open angle glaucoma (POAG). Studies have shown that TGF-beta 2 influences cultured trabecular meshwork cells, and it reduced outflow facility when perfused into cultured horse equine anterior segments. In POAG, elevated expression of Gremlin by TM cells inhibited BMP4 antagonism of TGF-beta 2 and led to increased extracellular matrix deposition and elevated IOP.
Gene Name	TGFB2
Immunogen	Expression system for standard: NS0; Immunogen sequence: A303-S414
Cross-reactivity	There is no detectable cross-reactivity with other relevant proteins.
Sample Type	cell culture supernatants, serum and plasma (heparin, EDTA, citrate).
Capture antibody\|Detection antibody	monoclonal antibody from mouse\|polyclonal antibody from goat
Storage	Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)
Anticoagulant	heparin, EDTA or citrate
Gene Full Name	Transforming growth factor beta-2
Molecular Weight	47748 MW
Protein Function	TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.
Subcellular Localization	Secreted.
Protein Name	Transforming growth factor beta-2
Sequence Similarities	Belongs to the TGF-beta family.

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