ArtNr |
BOS-EK0311-EQ |
Hersteller |
Boster
|
Menge |
96 wells/kit, with removable strips. |
Kategorie |
|
Typ |
Elisa-Kit |
Applikationen |
ELISA |
Specific against |
Horse |
Sensitivity |
<2 pg/ml |
ECLASS 10.1 |
32160605 |
ECLASS 11.0 |
32160605 |
UNSPSC |
41116126 |
Alias |
Bone morphogenetic protein 2 ;BMP2 ; |
Lieferbar |
|
Manufacturers Product Category |
PicoKine® ELISA Kits |
Manufacturers Research Category |
Angiogenesis, Cancer, Cardiovascular, Cytoskeleton/ECM, Extracellular Matrix, Growth Factors, Growth Factors/Hormones, Neural Stem Cells, Secreted, Signal Transduction, Signaling Pathways, Stem Cells, Structures, TGF Beta |
Short Description |
Horse equine BMP-2 ELISA Kit PicoKine® (96 Tests). Quantitate Horse BMP2 in bone tissue, cell culture supernatants and serum. Sensitivity: 2pg/ml. |
Description |
Horse equine BMP-2 ELISA Kit PicoKine® (96 Tests). Quantitate Horse BMP2 in bone tissue, cell culture supernatants and serum. Sensitivity: 2pg/ml. |
Background |
Bone morphogenetic protein-2 (BMP-2, BMP 2A) belongs to the transforming growth factor beta (TGF-beta) superfamily. It is thought to be involved in cartilage and bone formation during embryogenesis, but may have additional functions in morphogenesis as implied by its expression in various organs and embryonic tissues of mice.1 BMP-2 has been identified as a candidate mediator of retinoid activity. BMP-2 protein induces medulloblastoma cell apoptosis, whereas the BMP-2 antagonist noggin blocks both retinoid and BMP-2-induced apoptosis. BMP-2 also induces p38 mitogen-activated protein kinase (MAPK), which is necessary for BMP-2 and retinoid-induced apoptosis.2 Bone morphogenic proteins (BMPs) are known to promote osteogenesis, and clinical trials are currently underway to evaluate the ability of certain BMPs to promote fracture-healing and spinal fusion.3 The standard product used in this kit is recombinant horse equine BMP-2, constituting dimer by two chains of 114 amino acids with the molecular mass of 26KDa. |
Gene Name |
BMP2 |
Immunogen |
Expression system for standard: CHO; Immunogen sequence: Q283-R396 |
Cross-reactivity |
There is no detectable cross-reactivity with other relevant proteins. |
Sample Type |
bone tissue, cell culture supernatants and serum. |
Capture antibody|Detection antibody |
monoclonal antibody from mouse|polyclonal antibody from goat |
Storage |
Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.) |
Gene Full Name |
bone morphogenetic protein 2 |
Molecular Weight |
44702 MW |
Protein Name |
Bone morphogenetic protein 2 |
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