ArtNr |
BOS-PA1131 |
Hersteller |
Boster
|
Menge |
100 ug/vial |
Kategorie |
|
Typ |
Antibody Polyclonal |
Format |
Lyophilized |
Applikationen |
WB, IHC |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
GM181 antibody, IgLON family member 1 antibody, IGLON1 antibody, OBCAM antibody, OPCM antibody, OPCM_HUMAN antibody, OPCML antibody, Opiate binding cell adhesion molecule antibody, Opioid binding cell adhesion molecule antibody, Opioid binding protein/cell adhesion molecule antibody, Opioid binding protein/cell adhesion molecule-like antibody, Opioid binding protein/cell adhesion molecule-like preprotein antibody, Opioid-binding cell adhesion molecule antibody, Opioid-binding protein/cell adhesion molecule antibody |
Similar products |
GM181 antibody, IgLON family member 1 antibody, IGLON1 antibody, OBCAM antibody, OPCM antibody, OPCM_HUMAN antibody, OPCML antibody, Opiate binding cell adhesion molecule antibody, Opioid binding cell adhesion molecule antibody, Opioid binding protein/cell adhesion molecule antibody, Opioid binding protein/cell adhesion molecule-like antibody, Opioid binding protein/cell adhesion molecule-like preprotein antibody, Opioid-binding cell adhesion molecule antibody, Opioid-binding protein/cell adhesion molecule antibody |
Lieferbar |
|
Background |
Opioid-binding protein/cell adhesion molecule-like(OPCML), (also called opioid-binding cell adhesion molecule(OBCAM). OPCML is a member of the IgLON family of immunoglobulin(Ig) domain-containing glycosylphosphatidylinositol(GPI)-anchored cell adhesion molecules, as an excellent candidate for the 11q25 ovarian cancer TSG in EOC. The OPCML gene comprises 7 exons, spans approximately 600 kb, and is transcribed from telomere to centromere . And due to the lack of transmembrane domains necessary for signal transduction, it is improbable that OBCAM acts independently as an opioid receptor; more likely, it plays an important accessory role in opioid receptor function. |
Concentration |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Contents |
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
Cross reactivity |
No cross reactivity with other proteins |
Description |
Rabbit IgG polyclonal antibody for Opioid-binding protein/cell adhesion molecule(OPCML) detection. Tested with WB, IHC-P in Human; Mouse; Rat. |
Gene full name |
Opioid-binding protein/cell adhesion molecule |
Gene name |
OPCML |
Immunogen |
A synthetic peptide corresponding to a sequence at the C-terminus of human OPCML(294-312aa YTCVATNKLGNTNASITLY), identical to the related rat and mouse sequences. |
MW |
38008 MW |
Predicted reactivity |
Hamster |
Protein function |
Binds opioids in the presence of acidic lipids; probably involved in cell contact. |
Protein name |
Opioid-binding protein/cell adhesion molecule(OBCAM/OPCML/Opioid-binding cell adhesion molecule) |
Purification |
Immunogen affinity purified. |
Recommended detection ystems |
Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P). |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Research category |
|neuroscience|cell adhesion proteins|membrane proteins| neuroscience|neurotransmission|receptors / channels|gpcr|opioid receptors| cancer|oncoproteins/suppressors|tumor suppressors |
Sequence similarities |
Belongs to the immunoglobulin superfamily. IgLON family. |
Storage |
At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for a longer time.Avoid repeated freezing and thawing. |
Subcellular localization |
Cell membrane ; Lipid-anchor, GPI-anchor . |
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