Anti-Phospho-Histone H3 (Thr11) H3F3A Rabbit Monoclonal Antibody, Clone#RM164

Epigenetics and Nuclear Signaling, Histones

Boster Bio Anti-Phospho-Histone H3 (Thr11) H3F3A Rabbit Monoclonal Antibody, Clone#RM164 (Catalog # P06819-3). Tested in WB, ELISA, Luminex applications. This antibody reacts with Human, Vertebrates.

Monoclonal

50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

A phospho-peptide corresponding to Phospho-Histone H3 (Thr11)

Protein A affinity purified from an animal origin-free culture supernatant

Histone H3.3

Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.