ArtNr |
BOS-P06400 |
Hersteller |
Boster
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody |
Format |
Liquid |
Applikationen |
IF, ELISA, IHC-P |
Specific against |
Human, Mouse, Rat |
Host |
Rabbit |
Isotype |
IgG |
Sensitivity |
<15pg/ml |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
CNOT2;CDC36;NOT2;HSPC131;MSTP046;CCR4-NOT transcription complex subunit 2;CCR4-associated factor 2 |
Lieferbar |
|
Manufacturers Product Category |
Primary Antibodies |
Manufacturers Research Category |
Epigenetics and Nuclear Signaling, Mediator Complex, Transcription |
Short Description |
Boster Bio Anti-Phospho CNOT2 (Ser101) Antibody (Catalog# P06400). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat. |
Description |
Boster Bio Anti-Phospho CNOT2 (Ser101) Antibody (Catalog# P06400). Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat. |
Gene Name |
CNOT2 |
Clonality |
Polyclonal |
Concentration |
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Contents |
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Application Details |
Immunohistochemistry, 1:100 - 1:300 ELISA, 1:10000 Not yet tested in other applications. |
Immunogen |
A peptide derived from human CNOT2 around the phosphorylation site of Ser101. Immunogen sequence location: 67-116 |
Purification |
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
Storage |
Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Gene Full Name |
CCR4-NOT transcription complex subunit 2 |
Molecular Weight |
59738 MW |
Protein Function |
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity. |
Subcellular Localization |
Cytoplasm. Nucleus. |
Tissue Specificity |
Ubiquitous. Highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes. |
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