Alias |
Tumor necrosis factor receptor superfamily member 10D,Decoy receptor 2,DcR2,TNF-related apoptosis-inducing ligand receptor 4,TRAIL receptor 4,TRAIL-R4,TRAIL receptor with a truncated death domain,CD264,TNFRSF10D,DCR2, TRAILR4, TRUNDD,UNQ251/PRO288, |
Description |
Monoclonal, 01 antibody for DCR2/TNFRSF10D detection. Host: Mouse.Size: 100ug/vial. Tested applications: IHC. Reactive species: Human. DCR2/TNFRSF10D information: Molecular Weight: 41823 MW; Subcellular Localization: Membrane; Single-pass type I membrane protein; Tissue Specificity: Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart. |
Protein function |
Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF- kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. |