ArtNr |
BOS-M03529-Dyl550 |
Hersteller |
Boster
|
Menge |
100 ug/vial |
Kategorie |
|
Typ |
Antibody Primary |
Format |
Liquid |
Applikationen |
FC |
Clon |
15F10 |
Specific against |
Human |
Host |
Mouse |
Isotype |
IgG1 |
Konjugat/Tag |
DyLight 500 |
Citations |
1. Garcia-Heredia JM, et al. Specific nitration of tyrosines 46 and 48 makes cytochrome c assemble a non-functional apoptosome. FEBS Lett, 2012 Jan 20. <br/>2. Rajagopal BS, et al. The hydrogen-peroxide-induced radical behaviour in human cytochrome c-phospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant. Biochem J, 2013 Dec 15.<br/>3. Simon M, et al. Versatility of non-native forms of human cytochrome c: pH and micellar concentration dependence. J Biol Inorg Chem, 2013 Jan.<br/> |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Cytochrome c; CYCS; CYC |
Lieferbar |
|
Specificity |
No cross reactivity with other proteins. |
Manufacturers Product Category |
Primary Antibodies, Mouse Monoclonal Antibodies |
Manufacturers Research Category |
Apoptosis, Apoptotic Markers, Cancer, Cancer Metabolism, Cardiovascular, Cell Biology, Cell Death, Cytochromes, Energy Metabolism, Energy Transfer Pathways, Integration Of Energy, Integration Of Energy Metabolism, Invasion/Microenvironment, Lipases, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Oxidative Phosphorylation, Pathways and Processes, Signal Transduction |
Short Description |
Boster Bio Anti-Human Cytochrome C DyLight® 550 conjugated CYCS Antibody (monoclonal, 15F10) catalog # M03529-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human. |
Description |
Boster Bio Anti-Human Cytochrome C DyLight® 550 conjugated CYCS Antibody (monoclonal, 15F10) catalog # M03529-Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human. |
Background |
CYCS is also known as CYC, HCS or THC4. This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it accepts electrons from cytochrome b and transfers them to the cytochrome oxidase complex. This protein is also involved in initiation of apoptosis. Mutations in this gene are associated with autosomal dominant nonsyndromic thrombocytopenia. Numerous processed pseudogenes of this gene are found throughout the human genome. |
Gene Name |
CYCS |
Application Details |
Flow Cytometry, 1-3μg/1x106 cells |
Clonality |
Monoclonal |
Concentration |
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure. |
Contents |
Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3. |
Immunogen |
E.coli-derived human Cytochrome C recombinant protein (Position: G2-E105). Human Cytochrome C shares 91% amino acid (aa) sequence identity with both mouse and rat Cytochrome C. |
Cross-reactivity |
No cross-reactivity with other proteins. |
Storage |
At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light. |
Gene Full Name |
cytochrome c, somatic |
Protein Function |
Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. |
Subcellular Localization |
Mitochondrion intermembrane space. Loosely associated with the inner membrane. |
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