ArtNr |
BOS-M01148 |
Hersteller |
Boster
|
Menge |
100 ug |
Kategorie |
|
Typ |
Antibody Monoclonal |
Format |
Liquid |
Applikationen |
FC, IF, IHC, ELISA |
Clon |
LPFS2/1611 |
Specific against |
Human (Homo sapiens) |
Host |
Mouse |
Isotype |
IgG1 Kappa |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
CD27 antigen;CD27L receptor;T-cell activation antigen CD27;T14;Tumor necrosis factor receptor superfamily member 7;CD27;CD27;TNFRSF7; |
Lieferbar |
|
Manufacturer - Category |
Primary Antibodies, Monoclonal Antibodies, 2279 |
Storage Conditions |
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
Observed Molecular Weight |
29137 MW |
Clonality |
Monoclonal |
Application Details |
ELISA (For coating, order antibody without BSA) Flow Cytometry (1-2ug/million cells) Immunofluorescence (1-2ug/ml) Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined. |
Manufacturer - Gene Name |
CD27 |
Gene Full Name |
CD27 antigen |
Background |
Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis. |
Immunogen |
Recombinant full-length human CD27 protein |
Contents |
Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
Purification |
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G. |
Concentration |
Purified antibody with BSA and azide at 200ug/ml |
Manufacturer - Research Category |
Adaptive Immunity, Cancer, Cytokines, Hematopoietic Progenitors, Immunology, Innate Immunity, Lymphoid, Stem Cells, T Cells, T Lymphocytic Lineage, TNF Superfamily, Tumor Immunology |
Protein Function |
Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1. |
Subcellular Localization |
Cell Surface |
Short Description |
Boster Bio Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Monoclonal Antibody (Catalog # M01148). Tested in ELISA, Flow Cytometry, IF, IHC applications. This antibody reacts with Human. |
Description |
Boster Bio Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7) Monoclonal Antibody (Catalog # M01148). Tested in ELISA, Flow Cytometry, IF, IHC applications. This antibody reacts with Human. |
Tissue Specificity |
Found in most T-lymphocytes. |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.