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Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody

Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody

ArtNr	BOS-M01127
Hersteller	Boster
Menge	100 ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Format	Liquid
Applikationen	WB, IHC
Clon	HBB-19
Specific against	Human, Rat
Host	Rabbit
Isotype	IgG
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	14-3-3 protein sigma;Epithelial cell marker protein 1;Stratifin;SFN;HME1;
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Manufacturers Product Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturers Research Category	Adapters, Cell Type Marker, Cytoplasmic, Neural Signal Transduction, Neurology Process, Neuron Marker, Neuroscience, Signal Transduction, Signaling Pathways, Stem Cells, Synapse Marker
Short Description	Boster Bio Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody catalog # M01127. Tested in WB, IHC applications. This antibody reacts with Human, Rat.
Description	Boster Bio Anti-14-3-3 sigma SFN Rabbit Monoclonal Antibody catalog # M01127. Tested in WB, IHC applications. This antibody reacts with Human, Rat.
Gene Name	SFN
Application Details	WB 1:1000-1:2000 IHC 1:50-1:200
Clonality	Monoclonal
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Immunogen	A synthesized peptide derived from human 14-3-3 sigma
Purification	Affinity-chromatography
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	14-3-3 protein sigma
Molecular Weight	27774 MW
Protein Function	Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53..
Subcellular Localization	Cytoplasm. Nucleus. Secreted. May be secreted by a non-classical secretory pathway.
Tissue Specificity	Present mainly in tissues enriched in stratified squamous keratinizing epithelium.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ul

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Lieferung vsl. bis 04.10.2024

Express-Lieferung: 8 Tage sparen

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