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Anti-Ubiquitin C-Terminal Hydrolase 1 (UCHL1) Antibody

Anti-Ubiquitin C-Terminal Hydrolase 1 (UCHL1) Antibody

ArtNr	BOS-M01018-5
Hersteller	Boster
Menge	100 ul
Kategorie	Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Immunofluorescence Immunocytochemistry Autophagy Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IF, IHC, ICC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Horse (Equine), Pig (Porcine, Sus scrofa domesticus), Cattle (Bovine)
Host	Chicken
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Ubiquitin carboxyl-terminal hydrolase isozyme L1;UCH-L1;3.4.19.12;6.-.-.-;Neuron cytoplasmic protein 9.5;PGP 9.5;PGP9.5;Ubiquitin thioesterase L1;UCHL1;
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Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	24824 MW
Clonality	Polyclonal
Application Details	WB: 1:10, 000. IF/ICC and IHC: 1:1, 000.
Manufacturer - Gene Name	UCHL1
Gene Full Name	Ubiquitin carboxyl-terminal hydrolase isozyme L1
Immunogen	Recombinant full length human UCHL1 purified from E. coli.
Contents	Purified IgY preparation with 5mM NaN₃ at 20-30 mg/mL
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Protein Function	Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
Subcellular Localization	Cytoplasm. Endoplasmic reticulum membrane; Lipid-anchor. About 30% of total UCHL1 is associated with membranes in brain.
Short Description	Boster Bio Anti-Ubiquitin C-Terminal Hydrolase 1 (UCHL1) Antibody catalog # M01018-5. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Bovine, Equine, Human, Mouse, Pig, Rat.
Description	Boster Bio Anti-Ubiquitin C-Terminal Hydrolase 1 (UCHL1) Antibody catalog # M01018-5. Tested in IF, IHC, ICC, WB applications. This antibody reacts with Bovine, Equine, Human, Mouse, Pig, Rat.
Tissue Specificity	Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients.

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Menge: 100 ul

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Lieferung vsl. bis 01.05.2025

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