Anti-Acyl-coenzyme A thioesterase 8 ACOT8 Antibody

Primary Antibodies

Boster Bio Anti-Acyl-coenzyme A thioesterase 8 ACOT8 Antibody (Catalog # A09392). Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.

Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. Competes with BAAT (Bile acid CoA: amino acid N-acyltransferase) for bile acid-CoA substrate (such as chenodeoxycholoyl-CoA). Shows a preference for medium-length fatty acyl-CoAs By similarity. May be involved in the metabolic regulation of peroxisome proliferation.

Watanabe H., Biochem. Biophys. Res. Commun. 238:234-239(1997).
Liu L.X., J. Biol. Chem. 272:13779-13785(1997).
Jones J.M., J. Biol. Chem. 274:9216-9223(1999).

Polyclonal

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Synthesized peptide derived from internal of human ACOT8.

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

35914 MW

Cytoplasm. Peroxisome matrix. Predominantly localized in the peroxisome (PubMed:10092594, PubMed:15194431)..