ArtNr |
BOS-A08450 |
Hersteller |
Boster
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody |
Format |
Liquid |
Applikationen |
WB |
Specific against |
Human, Mouse |
Host |
Rabbit |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Ras-related protein Rab-7L1;Rab-7-like protein 1;Ras-related protein Rab-29;RAB29;RAB7L1; |
Lieferbar |
|
Manufacturers Product Category |
Primary Antibodies |
Short Description |
Boster Bio Anti-RAB7L1 RAB29 Antibody (Catalog # A08450). Tested in WB applications. This antibody reacts with Human, Mouse. |
Description |
Boster Bio Anti-RAB7L1 RAB29 Antibody (Catalog # A08450). Tested in WB applications. This antibody reacts with Human, Mouse. |
Gene Name |
RAB29 |
Clonality |
Polyclonal |
Concentration |
1 mg/ml |
Contents |
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application Details |
Western blotting: 1:500~1:3000 |
Immunogen |
Synthesized peptide derived from internal of human RAB7L1. |
Purification |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Storage |
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Gene Full Name |
Ras-related protein Rab-7L1 |
Molecular Weight |
23155 MW |
Protein Function |
Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans- Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection.. |
Subcellular Localization |
Cell membrane ; Lipid-anchor ; Cytoplasmic side. Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus. Golgi apparatus, trans-Golgi network. Vacuole. Cytoplasm, cytoskeleton. Colocalizes with LRRK2 along tubular structures emerging from Golgi apparatus (By similarity). Colocalizes with GM130 at the Golgi apparatus (PubMed:22042847). Colocalizes with dynamic tubules emerging from and retracting to the Golgi apparatus (PubMed:22042847). Colocalizes with TGN46 at the trans-Golgi network (TGN) (PubMed:24788816). In Salmonella enterica serovar Typhi (S.Typhi) infected epithelial cells, is recruited and colocalized with both S.Typhi-containing vacuoles and dynamic tubules as well as those emerging from the vacuole toward the cell periphery (PubMed:22042847).. |
Tissue Specificity |
Ubiquitous.. |
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